Skip to content
View inoue0426's full-sized avatar
🤔
🤔

Block or report inoue0426

Block user

Prevent this user from interacting with your repositories and sending you notifications. Learn more about blocking users.

You must be logged in to block users.

Maximum 250 characters. Please don’t include any personal information such as legal names or email addresses. Markdown is supported. This note will only be visible to you.
Report abuse

Contact GitHub support about this user’s behavior. Learn more about reporting abuse.

Report abuse
inoue0426/README.md

Yoshitaka Inoue

PhD Candidate in Computer Science at the University of Minnesota
Pre-doctoral Fellow at NLM / NCI, National Institutes of Health

Representation learning and structured machine learning for therapeutic response modeling,
computational drug discovery, and precision medicine.

🌐 Website · 📄 CV · 🎓 Google Scholar · 🧬 ORCID · 💼 LinkedIn


Research

My research develops machine-learning methods for modeling therapeutic response across molecular, cellular, and patient contexts. I am particularly interested in predictive representations, structured biological knowledge, and robust modeling under intervention.

Research Directions

  • Representation learning — learning predictive molecular, cellular, and patient representations that preserve treatment-relevant biological context.
  • Perturbation / response modeling — modeling treatment-conditioned changes in biological state and generalizing response predictions across drugs, cells, and patient contexts.
  • Structured / causal modeling — using biological structure and causal principles to improve interpretability, robustness, and generalization under intervention.

My PhD work follows a progression from interpreting drug response, to reasoning across biomedical evidence, to learning treatment-conditioned representations for response prediction.

Featured Projects

Attention-guided gene assessment of drug response using a drug–cell–gene heterogeneous network.

Reliable multi-agent aggregation for biomedical evidence synthesis and computational drug discovery.

Treatment-Conditioned Representation Learning

Ongoing thesis research on predictive representations for therapeutic perturbation and patient-response modeling.

More projects and publications are available on my academic website.

Research Infrastructure

I maintain a small set of open-source repositories for organizing research, evaluating ideas, and reusing scientific tools:

  • research_ideas — capture, compare, and evaluate research questions before committing substantial research time.
  • research_log — preserve research decisions, lessons, negative results, and open questions.
  • research_toolbox — reusable utilities and templates for computational biology and scientific workflows.
  • awesome-computational-biology — curated databases, software, datasets, papers, and resources in computational biology.

Together, these repositories support a lightweight workflow from existing resources → research ideas → projects and experiments → lessons and reusable tools.

Current Affiliations

  • University of Minnesota — PhD Candidate, Computer Science and Engineering
  • National Library of Medicine / National Cancer Institute, NIH — Pre-doctoral Fellow
  • Location: Bethesda, Maryland

Methods and Tools

Python PyTorch PyTorch Geometric Graph Neural Networks Representation Learning Single-Cell Analysis Docker Linux

Pinned Loading

  1. awesome-computational-biology awesome-computational-biology Public

    Awesome list of computational biology.

    Python 153 18

  2. drGT drGT Public

    Jupyter Notebook 1 2

  3. paper-summary paper-summary Public

    1

  4. DrugAgent DrugAgent Public

    Python 1 1